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A close-up of sliced pork medallions with a dark, glossy sauce on a white plate.

Crockpot Pork Tenderloin

Tender pork tenderloin slow-cooked in a tangy barbecue sauce until juicy and flavorful.
Prep Time 10 minutes
Cook Time 4 hours
Total Time 4 hours 10 minutes
Course Main Course
Cuisine American
Servings 4 servings

Ingredients
  

  • 2 lb pork tenderloin trimmed (usually two 1 lb pieces), about 900g
  • 2 cups barbecue sauce 480 ml
  • 1 tbsp spicy brown mustard 15 ml
  • 2 tsp chili powder 4g
  • ½ tsp kosher salt 3g

Instructions
 

  • Place the pork tenderloins in the bottom of a 6-quart slow cooker.
  • In a small bowl, whisk together the barbecue sauce, mustard, chili powder, and salt until combined.
  • Pour the sauce mixture evenly over the pork tenderloins.
  • Cover the slow cooker and cook on LOW for 4 hours or on HIGH for 2 to 2.5 hours.
  • Check for doneness with a meat thermometer. The pork is ready when the internal temperature reaches 145°F (63°C) at the thickest part.
  • Carefully transfer the pork from the slow cooker to a cutting board.
  • Let the pork rest for at least 3 minutes before slicing.
  • Slice the tenderloin into medallions and serve warm, drizzled with the extra sauce from the crockpot.

Notes

Pork Temperature: For food safety, pork must reach an internal temperature of 145°F (63°C) and rest for 3 minutes before serving.
Sauce Variations: Feel free to add a pinch of smoked paprika or a teaspoon of Worcestershire sauce to the barbecue mixture for a different flavor profile.
Checking Doneness: Cooking times can vary between slow cooker models. Always use a meat thermometer for an accurate reading to avoid overcooking the pork.
Keyword barbecue, crockpot pork tenderloin, pork, slow cooker, weeknight dinner